The first was while we were living in Spain. (Father was in the Air Force.) We took a road trip up to France, southern Germany, Switzerland (Matterhorn, Eigers, etc.), Austria, down through northern Italy, boat from Italy to Barcelona and then back to Madrid.
Last year we went on a roadtrip around Spain. Started in southern Spain (Malaga, Cordoba, Sevilla, Gibralter), went along the eastern coast up to Barcelona, then along the northern coast of Spain to A Coruna, then down to Madrid. Amazing trip.
Question: If cost isn't an issue, but you have health-related issues - why not do an extended cruise to various international locations?