Bigger:
Miami 1990: biggest win in program history, key to Ty winning the Hiesman
Utah 2008: a win here gets us into the BCS and just as importantly, keeps utah from beating Alabama (they're biggest win ever)
TCU/FSU 2009: these games kept us from a truly special season
Washington 1996: a win here puts us in a Bowl Alliance
Game, maybe even the national championship game
Equal in importance:
Wyoming and K State 1996
Hawaii 2001
Utah 2006