Overall fantastic series, great characters, plot lines, writing, etc.
Favorites:
Season - 4 (and then 2, 1, 3, 5)
Characters - Omar, Michael, Bubbs, the season 4 kids in general, Jimmy, the Bunk
Deaths - most rewarding - Stringer Bell, Cheese; saddest - Bodie w/ Wallace and Omar a close second
Season 5 jumped the shark for me a bit with the made up serial killer plot. And coming off a high of season 4 that doesn't help, but overall still enjoyed wrapping up the series. Enjoyed how they wrap it up and show the lifecycle start all over again --> Duke becomes the new Bubbles, Michael becomes the new Omar, etc. The game is still the game, it doesn't change, just a new generation of kids.
Next I need to go back and binge Loki.