When you’re constantly running it makes it more difficult. If you’re passing lots the reads become more natural, timing with receivers is better, etc.
I actually think that was a contributing factor to TH4’s accuracy problems his sophomore year. The more tired you are the easier it is for mechanics to break down.
It may take him a few games, but I think he’ll be a better passer overall on the year, based on those thoughts. Hopefully he has a MSU type of game though against us.