Some think he's going to run the 40 in around 4.7. I think he's going to be faster than that - 4.6's for sure, possibly even in the 4.5's, or I've totally misjudged his speed.
There were two tight ends who are almost his size who ran around 4.7. Vance McDonald ran a 4.69 at 267 lbs. (Ziggy measured at 271). Nick Casa ran a 4.71 at 6-5 7/8 and 269 lbs. (almost exactly Ziggy's size). I haven't seen anyone call either of these guys freak athletes.
There were two O-linemen who ran right around 4.7. At over 300 lbs.
I think he's going to be low 4.6 at the worst. I think 4.55 isn't unreasonably optimistic.