If allowed, I'd set the max for defense and PKs at zero and increase your chances at getting a sleeper.

A couple of tips...

If there is anyone you definitely don't want (because of injury concerns, or you hate them, or whatever) make sure you put them on your do not draft list.

If there is anyone you do want outside of the top 20 players, move them up 10 or so spots in your ranking. That increases the chances that you will get them before someone drafts them.