For example, in OT, the starting defense switches to offense and vise versa. Would be fascinating. Dirty Dan Sorenson launching bombs, for example, with Josh Allen trying to cover the Honey Badger.
Another idea. Remember the game Minesweeper? You play OT on a numbered field--don't "detonate a mine" though or that player is out for the rest of the game.
Or, you play with a ball made out of raw meat and release an apex predator onto the field. You think Tyreek Hill his going to flash the peace sign at that hungry cheetah that is taking an angle on him?
Just trying to think like the master himself. The NFL has so many entertaining options.