All the wasps will be in the nest and you can kill them all. If you spray it in the daylight many wasps will not be in the nest and will just make more. They will not fly very far at night so if some get out...they will die because they will return very quickly. Stand on the 16 foot ladder with a NEW can of wasp spray and use the whole can on it.... you will be wasp free the net morning then you can spray it with a water hose to knock it down off the house.
Be careful as WASP STINGS hurt.