1. I would divide it into two 64-team leagues, basically P5 and G5, with a few notable exceptions. Looking at you, BYU, some of the ACC schools, Rutgers, Oregon State, and Vanderbilt. Some schools will be kicked out of both P5 and G5, because that's just the way it has to be.
2. No more conferences: each league would divided into east and west divisions, with 32 teams in each. 12-game schedules (8 in-division games, 2 out-of-division games, and 2 out-of-league games) would favor historical rivalries and regional matchups.
3. Each league would have a 16-team championship tournament (the top 8 teams from each division), with seeding chosen by a transparent algorithm that factors in record, strength of schedule, and, to a much lesser extent, AP and coaches' polls. There would be relegation based on this: the 16 teams in the G5 championship tournament would replace the last 16 teams in the P5 group at the end of each year. The P5 and G5 champions both get a one-year exemption from relegation.
4. There will also be a 16-team invitation tournament for intriguing teams in either league that don't make the championship but want the extra practice and playing time of bowl season, kind of like the NIT.
5. "The U" and associated hand signs will be reserved for the University of Miami, and any fan from any other team that tries to appropriate it will be shunned from college football for a year.
6. Florida State, and any other team with an annoying chant or fight song, will be restricted to one chant/song per game, during a commercial break.
7. There will be an option to purchase streaming access to every single game.
8. There will be a highlight video department that produces NFL-style highlight videos within minutes after each game, available on Youtube.