The virus unleashes a huge Cytokine storm that leads to Pulmonary deterioration

Apr 7, 2020
11:05:19pm

Osteotome All-American

Counter intuitive but Autoimmune Rx such as hydroxychloroquine minimize the cytokine release and preserve pulmonary function

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Osteotome

Bio page: Osteotome
Joined: May 30, 2011
Last login: Jun 15, 2024
Total posts: 4,443 (20 FO)

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Messages

Author

Time

More theories and belief that Covid-19 is about O2 starvation and ventilators aren’t the solution

RdF3 All-American

4/7/20 10:34pm

We are being directed to minimize PEEP and O2 administration in these pts

gaspasscoug

4/7/20 10:40pm

Wow. One of the most intriguing articles I've read to date....

777

4/7/20 10:47pm

hydroxychloroquine decreases viral load. That would protect heme

OU Cougar

4/7/20 10:49pm

The virus unleashes a huge Cytokine storm that leads to Pulmonary deterioration

Osteotome

4/7/20 11:05pm

EM:RAP actually did a video podcast about this last week, specifically talking

Game Changer

4/7/20 11:17pm

So O2 and CPAP help but are discouraged but intubation seems to not help?

ArcticKat

4/8/20 12:26am

Emcrit also has been blogging about this.. seems this is more like

cougfanz

4/7/20 11:23pm

So is the hope we just pump the brakes on the vent and we might see a huge

777

4/7/20 11:41pm

No. The vents aren't really killing people, they just aren't helping the way

Game Changer

4/8/20 12:02am

Personally I’m not convinced they’re not contributing to increased mortality

cougfanz

4/8/20 12:04am

Are you ICU? You would definitely know better than I do. The sense I get from

Game Changer

4/8/20 12:13am

Nope. Cardiology. so rusty vent knowledge -

cougfanz

4/8/20 12:20am

Our vent survival rate so far has been much better than that. Small sample size.

dave

4/7/20 11:51pm

Good to hear. Ours is 50-50 with smaller size as well

cougfanz

4/8/20 12:04am

EM:RAP talks about mortality and intubation data here: problem is a ton of people still in the midst of it, so a lot of

Virginia Ute

4/8/20 12:02am

Good point. Such a slow death with this disease

cougfanz

4/8/20 12:04am

It’s really been crazy tracking some of my COVID admits from the ER. A few of them were like 92% on RA, looked good.

Virginia Ute

4/8/20 12:12am

Yeah sounds like we’ve had a lot of similar ones... doing relatively fine

cougfanz

4/8/20 12:25am

Are you treating with hydroxycloroquine and zpac,zinc? Willing to try ivermectin

CarolinaCoug

4/8/20 7:19pm

Are you treating with hydroxychloroquine? Zpac? Zinc?

CarolinaCoug

4/8/20 7:17pm

In the ER, no. In the ICU, yes, yes, no, no.

Virginia Ute

4/8/20 7:25pm

I've seen different numbers

bythenumbers

4/8/20 6:41am

Would Acetazolamide (mountain sickness) help? In combo with hydroxychloroquine?

happyhiker

4/8/20 9:11am

Thanks for posting this. Looks interesting.

ArcticKat

4/8/20 12:22am

So what’s the answer if this is it’s true progression?

pegushin

4/8/20 1:04am

I haven’t looked at the 2nd and 3rd tweet’s content, but the 1st tweet thread is

ldssdl

4/8/20 6:15am

Exactly. Stated as fact when there are huge leaps of logic.

FireCoug231

4/8/20 7:36am

Pretty interesting

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