If the WRs can run effective quick routes and get open then that will make all kinds of things possible. If, as in the recent past, they are unable to beat press coverage then Grimes will need to use screens and play action to buy time. I imagine that there will be some designed roll-outs to buy time for our WRs to get open.
If we can successfully run the ball (4 ypc or better) then the OLine will have done their job because 2nd and 6 and 3rd and 2 make life so much easier for Wilson.