We used a standard varmint trap (size for raccoon, opossum, skunks, etc) in the bushes by house, using an open can of catfood for bait. Found large skunk in the trap first thing in morning. The trick is to not get sprayed, so we threw an old blanket over the trap...that way if she sprayed, she'd get the worst of it. Left it totally covered and placed in back of pickup and drove to nearby pond. We dropped the covered trap into water deep enough it was totally submerged and left it under 5-10 minutes. I actually don't know what my buddy did with the carcass but it was his trap..

Relatively easy, but if done wrong could go badly..