There's a handful of good cost of living comparison tools.
The issue you'll run into is they mainly have the major metros so you'd have to get as close as you can. Here's a couple I've used in the past. You might just want to use a handful to get a general idea.
Moving to a new city? See how far your salary will go to maintain your standard of living using our Cost of Living Calculator. We offer you not only costs and income, but also information on schools, quality of life and demographics.
Compare the cost of living in two cities using the CNNMoney Cost of Living calculator. Determine if you could maintain your current standard of living in a different city.