in the majority of cases.

Lest any of you think this is directly related to the Newsweek article it isn't it :

"Clinical trials typically find that antidepressants are slightly better than placebo, at least in the short term. However, many researchers argue that this difference—about two points on a 52-point depression scale—is clinically imperceptible.

The question is what this minimal average difference means. There are two possibilities:

Most people experience just a tiny bit more improvement on the drug (a 12-point improvement) than they would on a placebo (a 10-point improvement); or
A small group of people experiences a larger effect from the drug, which is canceled out on average by the larger group of people who experience no effect.
In a new study, researchers have now concluded that it is the latter—in clinical trials, about 15% of people experienced a large effect from the antidepressant drug that they would not have received from the placebo. The authors write:

“The observed advantage of antidepressants over placebo is best understood as affecting a minority of patients as either an increase in the likelihood of a Large response or a decrease in the likelihood of a Minimal response.”
The paper appeared in BMJ. It was led by Marc Stone at the FDA’s Center for Drug Evaluation and Research. Also, it included famed Harvard placebo effect researcher Irving Kirsch, as well as researchers from Johns Hopkins and the Cleveland Clinic."