1- Don’t stay in a hotel with littles.
2- Don’t drive a ton. Stay closer to where the activities are.
3- Make a general plan but plan on modifications and changes. We usually plan 2-3 big activities and then have free days so kids can hang with friends or do whatever they want.
4- Plan some alone time with the wife. Go on a walk, Go to dinner, buy her a massage.
5- If your kids are too young, bring an older cousin or something to help with babysitting.
It does get easier as kids get older.
Good luck. Spend some more $.
Happy Wife, Happy Life.