Talks about the role insulin plays in weight gain and other hormones. The best thing about the book is it feels like the most comprehensive look at weight loss. He looks at every diet trend and explains why they work and where they fall short. Basically, they all have parts of the equation right.
Also talks about the food industry and government and how we have been wrong about what causes obesity for years. I would also recommend seeing "Fat Fiction" on Amazon prime. It's a documentary about how our government meal recommendations were totally wrong and actually lead to the obesity epidemic we have today. It's fascinating stuff.